Recent developments in the technology have presented viable dosage alternatives from oral route for pediatrics, geriatric, bedridden, nauseous or noncompliant patients. Fast dissolving films offer fast, accurate dosing in a safe, efficacious format that is convenient and portable, without the need for water or measuring devices. Fast dissolving films are typically the size of a postage stamp and disintegrate on a patient''s tongue in a matter of seconds for the rapid release of one or more APIs. The present research involves the formulation development of oral films of Famotidine by solvent casting method employing superdisintegrants like sodium starch glycolate, crosscarmellose sodium and crospovidone at different concentration levels. it was concluded that crospovidone (6%) could be used as a super disintegrant and HPMC E5 as a hydrophilic polymer in the formulation of fast dissolving oral films when compared to croscaramellose sodium and sodiumstarch glycolate in the formulations prepared by solvent casting method .
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